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KMID : 0379920000250020087
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Journal of The Korea Socity of Health Informatics and Statistics
2000 Volume.25 No. 2 p.87 ~ p.95
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Health Risk Assessment of Painting Workers Exposed to Toluene in Western Kyongnam Province
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이효민/Lee, Hyo Min
최은석/홍대용/김장락/양진규/강민정/강문국/Choi, Eun Seok/Hong, Dae Yong/Kim, Jang Rak/Yang, Jin Kyu/Kang, Min Jung/Kang, Moon Kuk
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Abstract
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This study was performed to assess the health risk of toluene expected in painting workplace. The subjects were 87 workers of 43 painting workplaces in western Kyongnam Province. They were monitored through personal air samplers during working time and the samples were analyzed by gas chromatography. Subchronic daily intake of toluene was induced using Monte-Carlo simulation. For the settlement of exposure variables, exposure time, exposure frequency and inhalation rate were establiched to 8 hours per day, 280 days per year and 20 m´/day, respectively. The air concentration of toluene, inhalation rate and body weight were used in the form of distribution values to calculate subchronic daily intake of toluene. The reference dose of toluene was induced using toxicity value from Integrated risk information system (IRIS) database. For risk characterization, Monte-Carlo simulation was used for the induction of subchronic hazard index. The results of risk assessment were summarized as follows:
Ⅰ. The air concentration of toluene was 39.313 ± 83.178 mg/m^3(mean ± standard deviation) ranging from 0.060 mg/m^3 to 444.108 mg/m^3. Among 87 subjects, only one exceeded threshold limit value(TLV-TWA).
Ⅱ. Subchronic daily intake of 25th and 50th percentile on toluene simulated by Monte-Carlo simulation were 0.13 mg/kg-day, 0.54 mg/kg-day, respectively.
Ⅲ. Inhalation reference dose of toluene was 0.13 mg/kg-day.
Ⅳ. Subchronic hazard index of 25th and 50th percentile on toluene simulated by Monte-Carlo simulation was 1.17, 2.69, respectively.
Adverse health effects of toluene to 65% of the workers would be expected in the selected painting workplaces because the hazard index of 35th percentile exceeded 1. So, we should not conclude there were no adverse health effects if it didn´t exceed TLV-TWA
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